FIDELITY OF HUMAN OVARIAN CANCER PATIENT-DERIVED XENOGRAFTS IN A PARTIALLY HUMANIZED MOUSE MODEL FOR PRECLINICAL TESTING OF IMMUNOTHERAPIES

Fidelity of human ovarian cancer patient-derived xenografts in a partially humanized mouse model for preclinical testing of immunotherapies

Background Immune Philips HID-PV /S checkpoint blockers (ICBs) have been approved by the Food and Drug Administration to be used alone in front-line therapies or in combination with other regimens for certain advanced cancers.Since ICB only works in a subset of patients and has limited efficacy in treating ovarian cancer (OVC), developing preclinic

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Analysis of Chlorine Gas Incident Simulation and Dispersion Within a Complex and Populated Urban Area Via Computation Fluid Dynamics

In some instances, it is inevitable that large amounts of potentially hazardous chemicals like chlorine gas are stored and Necklaces used in facilities in densely populated areas.In such cases, all safety issues must be carefully considered.To reach this goal, it is important to have accurate information concerning chlorine gas behaviors and how it

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